READERS SUMMARY: 1.  How does cortisol tie to a cell’s mass equivalence? 2. How does cortisol work daily in a human to wake us up? 3. How are the effects of cortisol stopped by AM sunlight? 4. How does cortisol link to NAD+ and circadian gene expression? 5. How does cortisol link circadian biology to mitochondrial handling of electrons in the cytochromes?   The circadian cycle of cortisol is critical in understanding optimal energy balance.  Cortisol directly alters a cell’s mass and volume.  Mass is directly tied to energy balance by E=mc2.  When you understand circadian biology, you get a much more complete picture of how the system works on a 24 hour basis. It turns out electrons control the coupling of biochemistry in life and understanding this helps making sense of why hormones become disrupted when electrons are not handled correctly.  I became a student of circadian biology when I saw the entire view from a 30,000 foot level. Our brain wakes up with a morning surge of cortisol. That is what turns our brain on at 6AM. VIP helps do this in long light cycles. VIP is highest at 6 AM and lowest at 6 PM when light levels […]

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READERS SUMMARY:   HOW DO MITOCHONDRIA REALLY WORK?   The funny thing about mitochondria is that everyone seems to know they are not working well in most modern diseases, but only a few know how mitochondria really work.  When most allopathic and alternative health practitioners talk about food, they talk about calories, carbohydrates, proteins, or lipids.  You know what is ironic about these discussions?  Open up any biochemistry book and see if there is carbohydrate, protein, or lipid transporter on the inner mitochondrial membrane.  There is not.  But there is this thing called the “electron transport chain“.  Why is it that nobody in allopathic medicine or alternative medicine talks about electrons? All foods are broken down into electrons. This means that the input to our mitochondria are electrons. Gary Taubes quoted Hans Krebs in Good Calories Bad Calories by saying, ‘All three major constituents of food supply carbon atoms’.  Most biochemists, clinicians, and scientists believe that metabolism is all about the carbon cycle.  I think most of you realize by now that I do not agree with this.  It is all about electrons.  This is why input to the mitochondrion is called ETC.  The second reason is that Gilbert Ling’s […]

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READERS SUMMARY 1.  How do prions cause disease? 2. How does light in the brain work? 3. Why red light is critical in the brain? 4.  How does Fronto-temporal dysplasia and Gliobastoma multiforman link together from a prion point of view? 5.  How do all these  neurologic and mental diseases link directly back to the gut?     Today in part two of our prion blog, you are going to learn the single most important function of life’s design using quantum biology is shape adaptation in both proteins and in DNA. Shape change dictates tissue optics and tissue optics are all tied to the proper thermodynamic view of life. The reason now should be intuitive. Any changes in geometry alters energy profiles and physiologic function. The innate ability to alter protein geometry in real time enables nature’s machines to operate with the utmost efficiency. Cells and tissues allow us to morph proteins to allow life to happen properly. When we do it incorrectly, disease and death emerges. It is not hard to understand……it is just hard to believe. We do it by altering atoms using electrons and photons to move their shapes. Electrons and protons are made from leptons and […]

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Prion protein in a microtubule

READERS SUMMARY 1.  WHAT IS A PRION AND WHY IS IT IMPORTANT? 2. BEWARE OF GARY TAUBES ? 3. HOW DOES SHAPE, SIZE, LENGTH OF PROTEIN SCALE TO BIOLOGIC ENERGY? 4. HOW DOES THE PHOTOELECTRIC EFFECT WORK IN US? 5. WHAT IS THE FOURTH PHASE OF MATTER, AND WHY DOES IT MATTER TO US?   Prion diseases, also known as spongiform encephalopathies, are fatal neurodegenerative diseases that can be sporadic, genetically determined, or acquired by a so called “infection”. One of the hallmarks of prion diseases is the cerebral accumulation of an abnormal form of prion protein (PrP), denoted PrPsc, which is derived from the normal cell surface glycoprotein (PrPc). Many of you might be unaware that the 1997 Noble Prize was given for this discovery.  Even fewer of you know that one of the “ancestral leaders” now running NuSi tried to obfuscate this scientist’s reputation in a 1986 article in Discover Magazine.  This is where I first heard of Gary Taubes.  It’s also why I became wary of his ideas and his writing methods and his goals.  He followed his first defamatory article in 1986 with another in 1997 by writing another highly inflammatory account of this discovery.  This was after Dr. […]

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  READERS SUMMARY:   We know evolution is the truth, but was Darwin fundamentally wrong about what drives biologic change?         Early on in the EMF series, one of my readers, Jason, asked me if I had jumped the shark when I said that biology gave the Nobel Prize to the wrong guy in 1978.  I remember messaging him on Facebook and telling him that I had a few more people to call out before I was done.  Changing a paradigm calls for slaying some core beliefs.  We have to attack the holiest of grails to see that evolution, the process that drives life, causes a thermodynamic problem.  Looking at it from a new perspective opens the doors to many answers that have eluded our species.   Today I am going after Darwin and all his neo-darwinian kling-ons, such as Sir Richard Dawkins.   If you are going to go big……I say do it in a large way .   I have told you I admire Nick Lane and Lynn Marguilis because they show that good thinking can lead to massive insights.  Lynn, using the theory of endosymbiosis, really went after the Darwin theory of evolution.  She made […]

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READER SUMMARY: Why are my blogs hard to read? How does magnetism help organize life?     “Truth cannot be brought down, rather the individual must make the effort to ascend to it. You cannot bring the mountain-top to the valley. If you would attain to the mountain-top you must pass through the valley, climb the steeps, unafraid of the dangerous precipices.”   This is why my blogs are tough to read.  To get better, you have to acquire as much knowledge as possible about how nature organizes life.   Life begins on the smallest stage, and the smallest stage is controlled by quantum mechanics.  It is not controlled by genes or gene products, but, in fact, is created from the quantum mechanisms in the universe.  The very same things that make stars make us.  Life, at its core,  is the same thermodynamic problem a star faces at creation. Kierkegaard said,  “Life can only be understood backwards but has to be lived forward.” He was a philosopher talking about his perception of life, but he actually stumbled into life’s “main paradox” without realizing it. Philosophers like to analyze life poetically by using existentialist thinking.   You will never solve life’s riddle […]

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READERS SUMMARY: How does a good question on the forum lead to a better answer to modern disease?     There is no trophy in health without a race…………for a new truth.   With many of you gathering with family this holiday weekend here is my little gift for you.  These two diseases just puzzle and confound many.  In this blog you will see a new way to look at these diseases.   Melasma is one of the most common problems millions of women face and they spend millions of dollars with cosmetics and dermatology consults to try to get rid of the problem.  Melasma is particularly common in women, especially pregnant women and those who are taking oral or patch contraceptives or hormone replacement therapy (HRT) medications.  It is also common in women who go through an early and fast paced menopause.  They also tend to have poor sleep as a stereotype for a deep reason. If you ask any dermatologist, if they are honest they will tell you it is one of the toughest 3 things they try to treat.  The main reason it is a tough disease is because we are not thinking about the pathway that […]

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READERS SUMMARY: 1.  IS ORGANIZATION OF A CELL MORE IMPORTANT THAN THE FOOD WE EAT? 2. HOW DOES NON OBVIOUS FACTORS DESTROY HEALTH IN SURPRISING WAYS? 3. HOW DOES GUT INTEGRITY TIE TO MITOCHONDRIAL FUNCTION? 4.  WHAT ARE THE 5 KEY FACTORS IN AUTOPHAGY? 5. HOW DOES KETOSIS LINK TO CIRCADIAN MISMATCHES?     A radical and transformative thought goes nowhere without the willingness to challenge convention. If you have a new idea, and it’s disruptive and you’re agreeable, then what are you going to do with that? Ideation without execution leads to the deletion of any great idea.  Your job is to find better ideas, mine is to cut holes in the ones you already  have.  Innovation requires embracing paradox. It requires you to be disagreeable.   I innovate by listening closely and mixing in curiosity.  This is why I see what others miss. I focus on what really matters to the organization of a cell to create life, and it’s not food that is the critical factor.  The organization of your cell’s architecture is important.  The factors that determine it are critical and there is no one thing that is critical.  The combination of factors and the details […]

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READERS SUMMARY:     WHAT DO YOU KNOW ABOUT THE ELECTRIC COMPANY BUILT INTO YOUR COLLAGEN?   This blog is intimately linked to the January through June 2014 webinars.  April’s webinar call “The Electric Company” is based upon the ideas in this blog. So todays blog starts via a discussion on the forum about raw foods.  you might want to review what I said in Brain gut 5 on this topic.   Hi JK I am Melanie, There is a product called Mega Hydrate created by Dr. Patrick Flanagan. The product is called hydride ions which are supposed to have an additional unpaired electron, making them potent anti oxidants. I am guessing these would improve redox potential. Dr. Flanagan stated raw foods and fresh cold pressed raw juices are full of hydride ions and thus raw food and juices would improve redox potential. I wonder if this is accurate?   I respond:  Hydride? If you understand Ling and Pollack’s work on water and charge separation you will understand that Flanagan is sadly mistaken. He clearly is assuming the reader knows nothing about physics and about water chemistry. Water becomes a hydride only in an alloy with a metal. In life, […]

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READERS SUMMARY: 1. In life can you overcome a hand of cards dealt to you that says you have a fatal genetic disease?     For those of you who listened to the March webinar you were able to meet Jeremy Thomley.  He is one of my new friends.  We have known each other for about 9 months.  He is an amazing person who you can find out a lot more about here:  Hyperlink to his website and blog.  Make sure you read his blog too.  His sculpting has to be seen to be believed.  He has another problem you might find hard to believe.  He has cystic fibrosis.  Cystic fibrosis (CF),  is an autosomal recessive genetic disorder that affects most critically the lungs, and also the pancreas, liver, and intestine. It is characterized by abnormal transport of chloride and sodium across an epithelium, leading to thick, viscous secretions. CF is caused by a frameshift mutation in the gene  for the protein cystic fibrosis transmembrane conductance regulator (CFTR).  The gene was identified in 1989 and is found at 7q31.2, the long arm (q) of chromosome 7 at position 31.2. An individual must inherit two defective cystic fibrosis genes, one from each parent, to have the disease. Each time two carriers of the disease conceive, there is a 25 percent chance of passing cystic fibrosis […]

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Many months ago, I was asked by someone to do a video testimonial for jackkruse.com. I planned to do it when I lost my last two pounds to my 50lb goal. Little did I know that would be 9 months later!

Take a listen to this story from Rob Hamilton. His story attests to the power of living Optimally.