READERS SUMMARY: 1.  WHAT HOLDS YOU CAPTIVE?   If you read the alternative health websites about adrenal fatigue and autoimmunity what do you seem to find consistently? Most people continue to believe that adrenal gland dysfunction is behind the idea we call “adrenal fatigue”.  That belief leads to many recommendations by alternative practitioners that are all over the place because their worldview of the etiology is playing on the wrong scale of knowledge. Recently on a popular private group of circadian biohackers, Brian K, made a very bold statement, “It’s not true adrenal supps do zero to help. They are the ONLY thing that help me and also apparently many other people. All you have to do is go to a popular supplement website and see there’s no shortage of positive reviews on glandulars.”  He went on to say, “Adrenal glands can and do break down and it’s not always a brain problem.”  I am sure that if you go to a supplement website they will surely tell you their products get positive reviews.  When your economic world is tied to false beliefs those beliefs generally become your worldview of reality. When I read this I realized why their is such a […]

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READERS SUMMARY: 1.  JET LAG IS THE BEST KNOWN CIRCADIAN MISMATCH:  HOW DO YOU BIOHACK IT? 2. WHAT EVOLUTIONARY ADAPTION DO BIRDS AND HUMANS SHARE ? 3. WHAT IS THE JET LAG Rx? 4.  WHY ARE SOLAR CYCLES TIED TO JET LAG RISK? 5.  ARE JET LAG, SOLAR CYCLES, AND COSMIC RADIATION SOMEHOW TIED TO HUMAN BEHAVIOR VIA WATER CHEMISTRY?     When we talk about human airplane flight let’s first talk about birds because they fly naturally.  So what do we have in common with them from an evolutionary perspective?  Birds and eutherians made it through the last extinction event 67 million years ago because they both had a built in extra capacity of mitochondria in their cells.  I spoke about this ability long ago in Cold Thermogenesis 5.  The reason both of these classes of animals had them were far different but this was the reason both made it through the KT event 67 million years ago.  Unlike humans, bird’s do not get jet lag when they fly. Have you ever wondered why?  What makes birds and us different?  Jet lag is the most well known circadian mismatch in humans.  This blog is going to teach a thing […]

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READERS SUMMARY: 1.  How discerning are you when “something popular” could be the wrong thing for you?   There was a recent blog and book written by two author’s on the net that I fell a few words should be said in random musing’s 4. The writer asserted, “There’s no evidence that too many carbs from fruit increase the risk of neurological disease. From sugar, yes, but not fruit or starchy plants like sweet potatoes (that I’m aware of, at least. I’d like to see any if it exists.)” Well there is a quite a bit of evidence that when your mitochondria are redox shifted,  sugar from any source will cause you some problems. If you thought that science was “certain” on this effect, well, that is just an error on the author’s part. It implies the author might have left a lot of biophysics and circadian biology out of their “certain” answer.  Dr. Bill Lagakos has pointed this many times over the last 6 months here.  It is clear when circadian biology is off what we expect to happen does not happen. After reading these writings I was reminded of a wonderful quote from physics that fits perfectly: “Scientific […]

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READERS SUMMARY: 1.  WHY DO MANY HAVE A PROBLEM WITH KETOSIS? 2.  HOW DOES SEASONAL AFFECTIVE DISORDER EXPLAIN THIS PHENOMENA? 3.  HOW DOES TECHNOLOGY SHORT CIRCUIT OUR MITOCHONDRIA? 4.  DO YOU CONFUSE DYSFUNCTION WITH IMMATURITY? 5.  CAN AN IMPERFECT HYPOTHESIS STILL BE DIRECTIONALLY ACCURATE?   Why do I have problems with ketosis?  This is a question I get asked a lot and a question I see asked in many other places online.  The answer isn’t an obvious one.  Most people think ketosis is a function of the amount of fat or protein you eat.  It is not.  The best brand of ketosis is the one that allows our brain and mitochondria to sense the correct circadian signals from our environment.  You have to have your circadian cycles and your food match or yoked to understand the context correctly.  If you only look at one and not the other it is akin to having one oar in a row boat.  You will spin in circles until you realize both need to match.  Ketosis without DHA can not generate enough IR light from your mitochondria to drive uncoupling.  This is why the CPT 1-a mutation exists in cold adapted humans.  This defect […]

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READERS SUMMARY     1. DO YOU THINK FOR YOURSELF OR DOES YOUR TRIBE SPEAK FOR YOU?   Here is a a nicely written blog on why you need to tighten up your thinking to tighten up your cells function.  Few people see how thinking changes your health trajectory.  In my opinion it is the most important factor in human health. Your world view has to be structured in principle on some specific doctrine which shapes how you function and view humanity. Embracing QED is akin to wearing steel-toed boots in a ballet-slipper world.   By Dr. Neil Billeaud   If everyone else jumped off a cliff… Humans are social creatures. We are born physically, neurologically, and epistemologically dependent on others, for evolutionary reasons Jack has previously explained. Therefore, we do not build our worldview directly from nature as all other animals do. We learn primarily from elaborate symbolic communication with other humans. It is a great shortcut that allows advanced knowledge to be additive across many lives and lifetimes. A uniquely human neurological adaptation. But our greatest asset is also our greatest blind spot. Since much of our knowledge is predominantly “absorbed” in this way, through language and concepts, rather […]

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READERS SUMMARY: 1. IS ORGANIZATION OF A CELL MORE IMPORTANT THAN THE FOOD WE EAT? 2. HOW DOES NON OBVIOUS FACTORS DESTROY HEALTH IN SURPRISING WAYS? 3. HOW DOES GUT INTEGRITY TIE TO MITOCHONDRIAL FUNCTION? 4. WHAT ARE THE 5 KEY FACTORS IN AUTOPHAGY? 5. HOW DOES KETOSIS LINK TO CIRCADIAN MISMATCHES?   A radical and transformative thought goes nowhere without the willingness to challenge convention. If you have a new idea, and it’s disruptive and you’re agreeable, then what are you going to do with that? Ideation without execution leads to the deletion of any great idea. Your job is to find better ideas, mine is to cut holes in the ones you already have. Innovation requires embracing paradox. It requires you to be disagreeable. I innovate by listening closely and mixing in curiosity. This is why I see what others miss. I focus on what really matters to the organization of a cell to create life, and it’s not food that is the critical factor. The organization of your cell’s architecture is important. The factors that determine it are critical and there is no one thing that is critical. The combination of factors and the details of how […]

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READERS SUMMARY: 1.  How does cortisol tie to a cell’s mass equivalence? 2. How does cortisol work daily in a human to wake us up? 3. How are the effects of cortisol stopped by AM sunlight? 4. How does cortisol link to NAD+ and circadian gene expression? 5. How does cortisol link circadian biology to mitochondrial handling of electrons in the cytochromes?   The circadian cycle of cortisol is critical in understanding optimal energy balance.  Cortisol directly alters a cell’s mass and volume.  Mass is directly tied to energy balance by E=mc2.  When you understand circadian biology, you get a much more complete picture of how the system works on a 24 hour basis. It turns out electrons control the coupling of biochemistry in life and understanding this helps making sense of why hormones become disrupted when electrons are not handled correctly.  I became a student of circadian biology when I saw the entire view from a 30,000 foot level. Our brain wakes up with a morning surge of cortisol. That is what turns our brain on at 6AM. VIP helps do this in long light cycles. VIP is highest at 6 AM and lowest at 6 PM when light levels […]

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READERS SUMMARY:   HOW DO MITOCHONDRIA REALLY WORK?   The funny thing about mitochondria is that everyone seems to know they are not working well in most modern diseases, but only a few know how mitochondria really work.  When most allopathic and alternative health practitioners talk about food, they talk about calories, carbohydrates, proteins, or lipids.  You know what is ironic about these discussions?  Open up any biochemistry book and see if there is carbohydrate, protein, or lipid transporter on the inner mitochondrial membrane.  There is not.  But there is this thing called the “electron transport chain“.  Why is it that nobody in allopathic medicine or alternative medicine talks about electrons? All foods are broken down into electrons. This means that the input to our mitochondria are electrons. Gary Taubes quoted Hans Krebs in Good Calories Bad Calories by saying, ‘All three major constituents of food supply carbon atoms’.  Most biochemists, clinicians, and scientists believe that metabolism is all about the carbon cycle.  I think most of you realize by now that I do not agree with this.  It is all about electrons.  This is why input to the mitochondrion is called ETC.  The second reason is that Gilbert Ling’s […]

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READERS SUMMARY 1.  How do prions cause disease? 2. How does light in the brain work? 3. Why red light is critical in the brain? 4.  How does Fronto-temporal dysplasia and Gliobastoma multiforman link together from a prion point of view? 5.  How do all these  neurologic and mental diseases link directly back to the gut?     Today in part two of our prion blog, you are going to learn the single most important function of life’s design using quantum biology is shape adaptation in both proteins and in DNA. Shape change dictates tissue optics and tissue optics are all tied to the proper thermodynamic view of life. The reason now should be intuitive. Any changes in geometry alters energy profiles and physiologic function. The innate ability to alter protein geometry in real time enables nature’s machines to operate with the utmost efficiency. Cells and tissues allow us to morph proteins to allow life to happen properly. When we do it incorrectly, disease and death emerges. It is not hard to understand……it is just hard to believe. We do it by altering atoms using electrons and photons to move their shapes. Electrons and protons are made from leptons and […]

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Prion protein in a microtubule

READERS SUMMARY 1.  WHAT IS A PRION AND WHY IS IT IMPORTANT? 2. BEWARE OF GARY TAUBES ? 3. HOW DOES SHAPE, SIZE, LENGTH OF PROTEIN SCALE TO BIOLOGIC ENERGY? 4. HOW DOES THE PHOTOELECTRIC EFFECT WORK IN US? 5. WHAT IS THE FOURTH PHASE OF MATTER, AND WHY DOES IT MATTER TO US?   Prion diseases, also known as spongiform encephalopathies, are fatal neurodegenerative diseases that can be sporadic, genetically determined, or acquired by a so called “infection”. One of the hallmarks of prion diseases is the cerebral accumulation of an abnormal form of prion protein (PrP), denoted PrPsc, which is derived from the normal cell surface glycoprotein (PrPc). Many of you might be unaware that the 1997 Noble Prize was given for this discovery.  Even fewer of you know that one of the “ancestral leaders” now running NuSi tried to obfuscate this scientist’s reputation in a 1986 article in Discover Magazine.  This is where I first heard of Gary Taubes.  It’s also why I became wary of his ideas and his writing methods and his goals.  He followed his first defamatory article in 1986 with another in 1997 by writing another highly inflammatory account of this discovery.  This was after Dr. […]

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What Others Are Saying

Many months ago, I was asked by someone to do a video testimonial for I planned to do it when I lost my last two pounds to my 50lb goal. Little did I know that would be 9 months later!

Take a listen to this story from Rob Hamilton. His story attests to the power of living Optimally.