Alzheimer’s

Can The Light Used In Eye Surgery Set The Stage For Alzheimer’s Disease?

Pharmacological treatments for Alzheimer’s disease (AD) have not resulted in desirable clinical efficacy over 100 years. Hydrogen peroxide (H2O2), a reactive and the most stable compound of reactive oxygen species, contributes to oxidative stress in AD patients.  What does elevated H2O2 do to neurons? Become an Optimal Klub Member or a Patron on Patreon.com to read the full blog.

By |August 1st, 2019|Alzheimer’s, Uncategorized|Comments Off on Can The Light Used In Eye Surgery Set The Stage For Alzheimer’s Disease?

Energy and Epigenetics 10: The Quantum Puzzle

Most of the science that gets done today gets done within a rigid set of rules applied, where you know exactly who your peers are, and things get evaluated according to a very strict set of standards. That works, when you're not trying to change the structure. But when you try to change the structure or paradigm of science, that system doesn't work very well. In fact, you usually make some enemies. Gilbert Ling is an example of somebody who didn't follow the rules and pissed a lot of people off. He pissed off so many people that they alienated his work, made sure he had no funding to continue on, and then allowed somebody to steal his work and gave that person the Nobel Prize in 2003. Today, we are going to unfold that story, because fundamentally this is why millions are dying from neolithic diseases today.

Energy and Epigenetics 6: Quantum Cell Theory, Life as a Collective Phenomena

This will probably be the most important blog in the entire Quilt. It is how I see the three fundamental laws of nature integrating and coordinating the physiologic function of animating life. It is how all life works as a collective phenomena.

Energy and Epigenetics 2: The Real DHA Story

We are all products of our environment. Our genes are the first draft of what we are created to be, but the experience those genes face (epigenetics) is how the novel of our life is really written. This blog is about how this experience begins to unfold in our species.

Energy & Epigenetics 1: The Infant Brain is Unique

Today, we begin to examine levee's 6, 14, and 26 in the Quilt document for the first time. We begin to show examples of these levee's by examining how the human brain forms and functions in an infant. This example will act as an analogy to help us understand many other processes as the blog series rolls on. There are many countervailing influences in life that on the surface confuse our intellect. They create the appearance of paradox, enigma, and myths, and mysteries. I find when we look at the world through the hull of a glass-bottom ship, to look through a kaleidoscope at the galaxies that exist on the edge of our mind, we begin to see the sense that nature makes from the chaos of the world. I like the irony that mysteries often create. Today, we are going to use some "other observations" we have all made to show you how the mysteries of our modern world might be solved asking better questions instead of settling for the answers we have been given. The Human Infant It is clear in modern medicine now that we can not have optimal human brain development unless we have a secure nutrient rich food supply for both mother and child. This relationship also needs to be maintained postnatally for several years after birth until neuralation is successful. It does appear in modern neurosurgery research that human brain development is programmed genetically to a certain extent, but is more malleable then we thought because of the new science findings of epigenetics. This is also more apparent in humans than other mammals because our brain is so complex that even small changes in functional regions can lead to massive clinical changes that become apparent as the child develops. Autism and spectrum disorders are a good example of this phenomena.

EMF 7: Quantum Prometheus

If you remember my podcast several years back, I told you the disease that got me interested in all this was osteoporosis. This is a disease I treat a lot as a spine surgeon. I discussed Wolff’s law in detail in the EMF 1 blog. When I realized that Wolff’s law was null and void in leptin resistance states in bone, something else radical appeared to me. I knew that Leptin Resistance signaled inflammation, and inflammation could be seen as a positive charge and loss of a negative charge on MRI’s, fMRI, and MEG studies. I also realized that MRI or NMR should show an increased flair signal on T2 weighted MRI images signifying an intracellular water loss coupled with a loss of collagen and of ATP. Collagen makes up the main protein of connective tissues in all mammals, typically 60–70{a7b724a0454d92c70890dedf5ec22a026af4df067c7b55aa6009b4d34d5da3c6} by weight. The water and collagen constitute a liquid crystalline matrix in which every cell in the body is embedded, making this system the ideal medium for intercommunication in eutherian mammals. Within this matrix we have learned about proton and electron superconduction that not only feed the underlying mechanistic pathways that most biochemistry recite but they also feed a rich “wet chemistry” that is fundamentally based upon special qualities of water. It turns out water has some prodigious quantum flexibility when it is confined in closed spaces that make it do some unique quirky things that no classic chemist would predict. These things are all predicted by quantum electrodynamic field theory. One such quirk is the use of water reverse micelles around proteins that increase enzyme action and kinetics by the order 10 to the 10th power based upon the pioneering work of Frank Mayer and Jim Clegg. Classic physics and chemistry thinks of water in its bulk form only because that is all the classic sciences can explain about it. In quantum coherence, where water acts as a total cohesive unit because it has infinite chemical freedom, water becomes highly structured chemically, from its bulk form to do some amazing things, to become extremely flexible in phase transitions between ice crystals and liquid crystals and gas vapor as it gets confined in small diameter nanotubes in our cells. Water dynamics and actions are quantumly altered as it is confined within nanotubes it develops properties that allow it to collectively work dynamically within reverse micelles and in proton superconducting cables that align along collagen in the cells cytoarchitecture to allow for super fast semiconduction. This has been reproduced by many physics and molecular biology researchers in electron photomicrographs and X-ray diffraction studies. The most amazing property water develops as it is confined in these nanotubes, it becomes a super catalyst that organic chemistry has missed, because it accounts for the energy of activation of biochemical reactions and enzymatic kinetics. It is not ATP that does this, ever!! ATP has another more critical function. It unfolds protein in cells to open water binding sites to form these super conduction cables to create 100{a7b724a0454d92c70890dedf5ec22a026af4df067c7b55aa6009b4d34d5da3c6} energy efficiency.

Brain Gut 16: Adrenal Fatigue Rx

What is Adrenal Fatigue at its core? Many websites will tell you it is an adrenal gland function problem that is best assayed by a salivary adrenal stress panel. I wont and I do not. The cause of adrenal fatigue is a brain injury at the hypothalamus all caused by bad signaling. My Adrenal Fatigue Rx is best called Metabolic Neurosurgery: It is all about energy and energy utilization that allows for perfect signaling of environmental signals. When your energy is bad your signaling falls off a cliff. The ASI is just like a gauge on a car. It tells you some info but it does not tell you why it is happening. How we understand adrenal dysfunction in 2012 has radically changed because of a relatively new science called neurohumoral-immunology. What does this mean? It means adrenal fatigue at its core is a brain illness and not an adrenal gland problem. What is the PVN? How do we know if our PVN is shut off? What are some of the symptoms? We can’t sleep, our guts do not work, our body composition goes way off, we sweat at the wrong times, we develop cognitive haze, blurred vision, migraines, and reactive hypoglycemia. Many times fatigue is only relieved by eating foods we should not. It also means we have lost allosteric control of leptin!

Circadian Biology Webinar

[show_if has_tag="No-Webinar-2012-08-August"]Buy Webinar[/show_if][show_if has_tag="Webinar-2012-08-August"]ACCESS YOUR WEBINAR[/show_if] We talk a lot on the blog about the brain-gut axis and the implications our gut has on our overall health, including: Most brain disease and neurodegenerative disorders start in the gut (tumors, autism, depression, high blood pressure, Alzheimer’s, hypertension, heart disease) start in the gut. Autoimmune diseases like MS starts in the [...]

Brain Gut 9: What Really Killed Michael Jackson

Today, we are going to dive into the gut flora story a bit deeper than we did in our first gut flora post to help you understand how a a change in gut flora might lead to changes in your health by altering your hormone panel. Obesity is an inflammatory brain condition. Where does the infection come from? The gut flora actually is what causes humans to become fat. It has to due with shear numbers and the species of bacteria in our gut. There is a particular flora that produces adiposity and obesity in humans. These bacteria make something called FIAF (Fasting induced adipose factor) that control this process. This factor blocks lipoprotein lipase (LPL) in fat cells. LPL allows us to convert dietary Free Fatty Acids carried in lipoproteins into neutral fats that are stored in adipocytes. Non Geeks: Our gut bacteria makes humans fat. Geek Alert: The FIAF is made by our liver, muscles, and our small bowel wall when food sources are in short supply. This is the signal to stop storing fat in our fat cells when food is scarce. What is not well appreciated by many is that the FIAF in our intestinal wall is controlled 100{a7b724a0454d92c70890dedf5ec22a026af4df067c7b55aa6009b4d34d5da3c6} by our gut flora. When we have a simplified gut flora it favors fat cell creation. When our gut flora is complex and healthy, it has 100 trillion cells with 250 species. We tend not to make fat in this instance either! Moreover, when the bacteria are active metabolically due to the presence of simple sugars, production of FIAF ceases, and fat creation is signaled. This implies that our gut flora is directly tied to fat creation in humans. The gut flora’s action is directly signaled to the brain via the afferent nerve fibers in the vagus nerve. In those newly created fat cells, a protein called leptin is also produced, and acts as a score keeper for the brain of how much fat is stored in the body. This messenger is sent to the brain around midnight when we are sleeping allowing the brain to assess total energy balance in the body.

Hormone CPC #1: DHEA

This blog post was created for my members who just heard my webinar on bioidentical and synthetic hormone replacement. It is specifically designed to further our discussions in that talk. DHEA has been an enigma to the public and to most physicians. I never once heard about this hormone in four years of medical school, seven years of residency or in any endocrinology lecture from my training. The general public did not learn about DHEA until 1996, when its benefits were mentioned in the media and several popular books that showed up on daytime TV shows. Most in mainstream medicine continued to ignore the science these books contained because they were not found in the usual ways via journals and continuing education classes. You actually had to be on the lookout for this information. With a busy medical practice, this is no easy task. DHEA became credible to the medical establishment when the New York Academy of Sciences published a book called DHEA and Aging. That book provided scientific validation for the many life-extending effects of DHEA.

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