Throughout the history of oncology research, in both the conventional and alternative cancer research realms, there has been a cause and effect relationship that has been largely ignored. The ability of a cell to divide, whether it be a malignant or non-malignant cell, is highly dependent on cell volume, as well as membrane potential. The collagen tensegrity system is piezo and flexoelectric and releases and absorbs light from the sun diurnally, and this is why cell volume and cancer are related; so when you lose energy and charge in a cell, the cell, mitochondria and nuclear membrane all enlarges. The temporal sequence of the enlargement is what differs. Mitochondrial morphology is one of the earliest changes because of changes in how electrons and protons are used in the matrix.