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What are some of the medical conditions that are associated with osteopenia or osteoporosis? 1. Excessive alcohol intake- greater than two drinks a day consistently will do it. 2. Tobacco use- This causes a 100 fold increase in bone loss. Oral tobacco is worse than inhaled smoke 3. Stress- any cause be it emotional, physical, mental, psychic all raise cortisol chronically and kill bone 4. Lack of physical activity increases obesity risk, which increases cortisol from leptin resistance 5. Low calcium intake or absorption from gastrectomy or low acid production from any reason 6. Reduced strength and activity due to a chronic illness or a sedentary life (checked with a grip test) 7. Small build or leanness naturally – correlates with BMI below 19 for women and men. 8. Asian women have a particular propensity to osteopenia genetically and from their diet. 9. Drug therapy, for example, long-term use of corticosteroids such as prednisone-used to treat rheumatoid arthritis, asthma, celiac disease, autoimmune diseases, Crohn’s disease, IBD, and ulcerative colitis. 10. Low Magnesium, strontium, boron, Vitamin D3, Vitamin K2, elevated PTH levels, low sex steroid levels, high insulin levels, low progesterone levels, any cause of a leaky gut. 11. Menopause 12. Andropause 13. Any cause of chronic inflammation (perimenopause can cause severe acute bone loss) 14. Disuse atrophy from any cause (space travel) 15. Paralysis 16. High carbohydrate diets 17. Veganism or a plant based diet. 18. A diet high in whole grain (carbohydrates) is especially risky due to mineral malabsorption in gut 19. A diet lacking in animal protein and animal fat and cholesterol. 20. Excessive use of statins and thyroid hormone can cause osteoporosis 21. Age and sex: the older one is predisposes to osteopenia. Women lose 1-3{a7b724a0454d92c70890dedf5ec22a026af4df067c7b55aa6009b4d34d5da3c6} of their bone density ever year after their last period. 22. Chronic endurance athletics of any type cause severe bone loss due to chronic cortisol elevations 23. Gastric bypass patients carry enormous osteopenic risks. 24. Severe liver or kidney disease; Renal insufficiency can lead to osteodystrophy. 25. Diabetes 26. People with scoliosis of unknown cause (idiopathic scoliosis) also have a higher risk of osteoporosis. I believe this is because most of these children have severe underlying Vitamin D deficiency and a leaky gut, but this has never been studied in the spine literature. Any time I see a scolisosi patient, I always screen for low sex steroid hormones, low Vitamin D levels, and low Carboxylated osteocalcin levels. Bone loss can be a feature of complex regional pain syndromes.as they develop over time. It is also more frequent in people with Parkinson’s disease and chronic obstructive pulmonary disease as well.