READERS SUMMARY: 1. A QUESTION DURING AN EDUCATIONAL CONSULT STIMULATES A DISCUSSION 2. HOW DOES ARTIFICIAL LIGHT DESTROY THE SIGNALING OF THE CORTISOL/DHEA/MELATONIN AXIS? 3. HOW DOES ARTIFICIAL LIGHT AFFECT THE GUT FLORA? 4. CAN ARTIFICIAL LIGHT AFFECT HUMAN BIOLOGY DIRECTLY? 5. IS BODY COMPOSITION TIED TO ARTIFICAL LIGHT AND IMPAIRED SLEEP CYCLES? [...]
Today, we are going to dive into the gut flora story a bit deeper than we did in our first gut flora post to help you understand how a a change in gut flora might lead to changes in your health by altering your hormone panel. Obesity is an inflammatory brain condition. Where does the infection come from? The gut flora actually is what causes humans to become fat. It has to due with shear numbers and the species of bacteria in our gut. There is a particular flora that produces adiposity and obesity in humans. These bacteria make something called FIAF (Fasting induced adipose factor) that control this process. This factor blocks lipoprotein lipase (LPL) in fat cells. LPL allows us to convert dietary Free Fatty Acids carried in lipoproteins into neutral fats that are stored in adipocytes. Non Geeks: Our gut bacteria makes humans fat. Geek Alert: The FIAF is made by our liver, muscles, and our small bowel wall when food sources are in short supply. This is the signal to stop storing fat in our fat cells when food is scarce. What is not well appreciated by many is that the FIAF in our intestinal wall is controlled 100{a7b724a0454d92c70890dedf5ec22a026af4df067c7b55aa6009b4d34d5da3c6} by our gut flora. When we have a simplified gut flora it favors fat cell creation. When our gut flora is complex and healthy, it has 100 trillion cells with 250 species. We tend not to make fat in this instance either! Moreover, when the bacteria are active metabolically due to the presence of simple sugars, production of FIAF ceases, and fat creation is signaled. This implies that our gut flora is directly tied to fat creation in humans. The gut flora’s action is directly signaled to the brain via the afferent nerve fibers in the vagus nerve. In those newly created fat cells, a protein called leptin is also produced, and acts as a score keeper for the brain of how much fat is stored in the body. This messenger is sent to the brain around midnight when we are sleeping allowing the brain to assess total energy balance in the body.
READERS SUMMARY: 1. What is a day in the life of a vacationing doctor like? 2. Accept that your epigenome is a loaded gun, and your lifestyle is the trigger. Your lifestyle can't change you. It reveals who you really are. 3. Is there an important difference between giving up on somethings and letting go to [...]
Many of you know I believe obesity if an inflammatory disease of the brain. Where this disease begins may surprise some of you. It begins in our gut flora. How does this happen? Read this link! Sub optimal bacteria which contain bacterial toxins called lipopolysaccharides (LPS) which are found in bacterial cell membranes. As gut LPS rises, it has been shown to cause a rise in serum leptin levels. Once leptin levels are raised high enough it stimulates SOCS 3 signaling in the hypothalamus to cause LR.
READERS SUMMARY: 1. WHAT ARE THE EVOLUTIONARY IMPLICATIONS OF A LEAKY GUT AS A POSITIVE ADAPTATION AT OUR SPECIES ORIGIN? 2. WHY DID BIPEDALISM ARISE BEFORE BRAINS IN HUMANS? 3. DID THE CLIMATE AND TECTONIC PLATES DICTATE THE EPIGENETIC CHANGES IN THOSE TRANSITIONAL PRIMATES? 4. DID RAPID CHANGES IN INNATE AND CELL MEDIATED IMMUNITY [...]
This blog post was created for my members who just heard my webinar on bioidentical and synthetic hormone replacement. It is specifically designed to further our discussions in that talk. DHEA has been an enigma to the public and to most physicians. I never once heard about this hormone in four years of medical school, seven years of residency or in any endocrinology lecture from my training. The general public did not learn about DHEA until 1996, when its benefits were mentioned in the media and several popular books that showed up on daytime TV shows. Most in mainstream medicine continued to ignore the science these books contained because they were not found in the usual ways via journals and continuing education classes. You actually had to be on the lookout for this information. With a busy medical practice, this is no easy task. DHEA became credible to the medical establishment when the New York Academy of Sciences published a book called DHEA and Aging. That book provided scientific validation for the many life-extending effects of DHEA.
READERS SUMMARY: 1. To discover the unknown we must use the known to guide our thoughts to see the future. 2. How should we think about evolution and health now? Counterintuitive is an axiomatic cognitive ability required for neurosurgical residency training and that is why I chose to tackle this problem in this fashion. 3. [...]
Buy Teleseminar If you struggle with eating disorders, obesity or diabetes; or if you have a family history of Alzheimer’s or Parkinson’s, this webinar is especially for you. The Epi-Paleo diet is different from the traditional Paleo template – it is rich in iodine and magnesium and gives you complete, optimal brain function. Remember, HEALTH STARTS IN [...]
READERS SUMMARY: 1. How does the fossil record prove that epigenetics is the most dominant factor in biology today? 2. How does this lack of insight create a huge mismatch for patients trying to get to Optimal? 3. Does epigenetics change they way we think? 4. Does the way we think alter our biology [...]
READERS SUMMARY: WHY IS IRON IMPORTANT? HOW DOES IT AFFECT LIFE AT A 30ft LEVEL MICROSCOPICALLY HOW DOES IT AFFECT LIFE AT A 30,000 ft LEVEL IN OUR OCEANS HOW DID EVOLUTION USE IRON TO PROTECT US AND OUR SPECIES? HOW DID A PROTECTIVE EFFECT BECOME A DEADLY DISEASE IN 50 YEARS RIGHT UNDER OUR [...]