Autism

EMF 2: Einstein, Meet Leptin

"You’ve got to work at living... when 99{a7b724a0454d92c70890dedf5ec22a026af4df067c7b55aa6009b4d34d5da3c6} of the globe works at dying daily; Denial of the truth will lead you into blind alleys. Let go of your paradigm, accept what nature designed, and embrace your ultimate potential" -Gretchen Bronson (starfish) Why is the clock the most important part of the story of life? Have you ever had a dream that seems so large in scope, it just seems like it just possibly cannot come to fruition? I have for the last 7 years. Today, I am going to share it with you. It is time. I believe all dreams come true, if we have the courage to pursue them. It is always easier to make a dollar off a dream, but it is a lot tougher to make a difference with one. I think EMF-2, is going to do just that for everyone. I told you all last March, on Sean Croxton’s underground internet radio show, and at Paleo FX 2012, that environmental mismatches all cause inflammation. Many of you found it a bold and interesting statement, but I never told you WHY. The reason I did not, was because I did not feel you were ready to understand my perspective, yet. Today that changes. When you do not understand someone’s perspective often times what they say sometimes sounds a bit 'bizarre' to you. The reason it does is because you have no frame of reference for understanding, primarily because you were never taught that space/time, might be the most critical factor in understanding trans-generational epigenetic biology today. That is going to change today as well.

BRAIN GUT 13: WHERE OPTIMAL MEETS ALL WORLD PERFORMANCE

READERS SUMMARY: 1. WHY IS DHA IN ITS EVOLUTIONARY PACKAGE THE KEY TO THE MASSIVE METABOLIC RATE OF THE HUMAN BRAIN AND HEART? 2. WHAT EVER MAKES CELLULAR SIGNALING "CLEAN" FOR AN ORGANISM LEADS TO OPTIMAL HEALTH. 3. WHAT THE BIOCHEMISTRY OF NEURAL LIPIDS MEANS FOR HOMO's SOLUTION? 4. WHAT ARE THE KEY METABOLIC NEUROLOGIC [...]

By Jack Kruse|September 27th, 2012|Autism, Breast Cancer, Cancer, Circadian Cycle, Cold Thermogenesis, Depression, Epi Paleo, Epigenetics, Heart Disease, Hormones & Methylation, Leaky Gut / Grain Brain, Live your Optimal Weight, Longevity Principles, Mitochondria, Nutrients and Supplements, Optimal Pillar 1, Optimal Pillar 2, Optimal Pillar 4, Series: Brain Gut, The Importance of Sleep, The Optimal Paleo Diet|Comments Off

Circadian Biology Webinar

[show_if has_tag="No-Webinar-2012-08-August"]Buy Webinar[/show_if][show_if has_tag="Webinar-2012-08-August"]ACCESS YOUR WEBINAR[/show_if] We talk a lot on the blog about the brain-gut axis and the implications our gut has on our overall health, including: Most brain disease and neurodegenerative disorders start in the gut (tumors, autism, depression, high blood pressure, Alzheimer’s, hypertension, heart disease) start in the gut. Autoimmune diseases like MS starts in the [...]

By Jack Kruse|September 11th, 2012|Alzheimer’s, Autism, Circadian Cycle, Depression, Heart Disease, Hormones & Methylation, HPA Axis, Inflammation, Leaky Gut / Grain Brain, Longevity Principles, The Importance of Sleep, The Optimal Paleo Diet, Webinars and Q&A Calls|Comments Off

BRAIN GUT 7: INTRO TO YOUR GUT MICROBIOME

Many of you know I believe obesity if an inflammatory disease of the brain. Where this disease begins may surprise some of you. It begins in our gut flora. How does this happen? Read this link! Sub optimal bacteria which contain bacterial toxins called lipopolysaccharides (LPS) which are found in bacterial cell membranes. As gut LPS rises, it has been shown to cause a rise in serum leptin levels. Once leptin levels are raised high enough it stimulates SOCS 3 signaling in the hypothalamus to cause LR.

Brain Gut #5: Paradigm Drifts Paradigm Shifts–Epi-Paleo Rx

Geeks: The implications of Brain Gut 4 mean that to develop a brain seafood is required part of the program to maintain it. Nutrients and many other environmental factors have also been found to influence epigenetic programing of our DNA either directly or indirectly via metabolic sensors. Peroxisomal proliferator-activated receptors (PPAR's), the vitamin D receptors, and the retinoid X receptors (RXR), and the retinoic acid receptors (RAR) are all examples of the nuclear receptors that interact with the brain cell membranes to control inflammation and metabolism all over our bodies. It turns out that PPAR's are the receptors that are at the crossroads of where inflammation and metabolism actually cross. These are specialized lipid sensors that pay attention to our balance of omega 6 and 3 levels. 3{a7b724a0454d92c70890dedf5ec22a026af4df067c7b55aa6009b4d34d5da3c6} of the human genome is directly or indirectly controlled by the endocrine functions of the Vitamin D system. This shows you how environmental signals are intertwined into the expression of DNA in humans. The Epi-Paleo Rx controls inflammation at a hormonal level in the brain better than the more famous paleo diet. Non Geeks: What we eat is really damn important when you have 3 lbs of lipid in your head called a brain. If you eat outside our design you get sick.

E=MC2: MAKING FACTOR X ACTIONABLE

READERS SUMMARY: 1. How does the fossil record prove that epigenetics is the most dominant factor in biology today? 2. How does this lack of insight create a huge mismatch for patients trying to get to Optimal? 3. Does epigenetics change they way we think? 4. Does the way we think alter our biology [...]

By Jack Kruse|May 26th, 2012|ADD / ADHD, Autism, Cancer, Circadian Cycle, Diabetes, Epigenetics, Heart Disease, Longevity Principles, Optimal Pillar 2, Series: Miscellaneous, The Importance of Sleep|120 Comments

TO B OR NOT TOO B……..OR IS IT PROTEIN?

READERS SUMMARY: 1. WHY IS PALEO PROTEIN CRITICAL TO CARTILAGE AND TENDON REPAIR? 2. HOW DOES PROTEIN HELP REPAIR CARTILAGE IN INJURY AND DEGENERATION? 3. WHY ARE B VITAMINS CRITICAL TO THE PALEO TEMPLATE? 4. WHY A PALEO TEMPLATE IS BEST FOR A PREGNANT MOM OR A YOUNG CHILD? Today, we are going to go [...]

By Jack Kruse|October 5th, 2011|Autism, Cancer, Depression, Diabetes, Epi Paleo, Epigenetics, HIIT - Heavy Weights, MS - Multiple Sclerosis, Nutrients and Supplements, Optimal Pillar 4, Optimal Pillar 5, Series: Miscellaneous, The Optimal Paleo Diet|45 Comments

Central Leptin Dominance: Part 2

Continuing on in the Central leptin series we will resume in Orlando, Florida. In Orlando, Dr. Myers, went on to say, "In addition to examining the molecular details and importance of specific LRb signals, we are dissecting the regulation and function of individual populations of LRb-expressing neurons and examining the role of leptin in the development of neural circuits. By understanding the totality of leptin action in this way we hope to decipher the mechanisms by which leptin regulates the predisposition to diabetes and other aspects of the metabolic syndrome." This statement carries huge implications. He has found that not only is leptin neurons somatotopically organized in the brain, but the leptin receptor also appears to be somatotopically organized into certain regions that wire and select certain neurons in the brain that modulate all parts of the obesity physiologic response. It also appears that this organization is different in men and women at the parvo-cellular nucleus in the hypothalamus. Certain parts of the receptor control total body glycemic control, others body weight and size, and others power the para-mammillary neurons to directly control fecundity, placental growth and oocyte maturation. The receptor even codes for gender differences! Men and women really are from Mars and Venus when it comes to obesity and fat deposition, and this explains why the endocrine response is different in men and women. We have known men and women have different leptin levels as adults but did not know how or why this happens. Now we do. We now are beginning to understand why it is the case as well. It helps explain why we see can see PCOS and stubborn weight gain together and why fat is distributed differently in both sexes.

By Jack Kruse|August 28th, 2011|Anorexia and Bulimia, Autism, Diabetes, Dyslexia, Endometriosis and PCOS, Epi Paleo, Epigenetics, Hormones & Methylation, Leaky Gut / Grain Brain, Live your Optimal Weight, Optimal Pillar 2, Series: Leptin, The Leptin Prescription|Comments Off

Your Gut, Neurotransmitters, and Hormones

READERS SUMMARY: 1. HOW YOUR GUT BRAIN AND RESPONSE OF YOUR BRAIN ARE ALL TIED TOGETHER? 2. WHAT ARE THE 4 MAIN NEUROTRANSMITTERS? 3. WHAT DO THEY DO AND MEAN? 4. WHAT AFFECTS THEIR PRODUCTION? 5. HORMONES ARE THE BRAINS ENDOCRINE SECRETION THAT TELLS YOU HOW YOUR EPIGENETIC SWITCHES ARE SET. 6. HOW WE USE [...]

The Leaky Gut Prescription

Well, we have talked about the gut in three other blogs so far. (1) Could It Be the Gut?: An Introduction to the Brain-Gut Axis, (2) Your VAP = Brain Gut Axis Function, and (3) Why Leaky Guts Lead to MS? Click those links or go to my home page under Brain Gut Axis and find each one for a quick review. We have hinted at the leaky gut as a cause of serious human disease in all those posts. Today we get to focus on the "leaky gut" and how we might offer to treat it. What is a leaky gut syndrome? It is the complex biochemical reactions that occur in the gut appear to be the genesis of where inflammation initially passes in to our body. We need to realize this and avoid eating the things that cause this inflammation. As I have said for close to five years now this means strict avoidance of omega 6's, all grains and especially wheat of any kind and very limited fructose (fruit or synthetic sources) The gut associated lymphatic tract (GALT) is the first place where our immune systems interact with the outside world. This occurs right below the intestinal brush border and is our first line of defense. It seems to me that evolution has dictated that this is precisely where the battle between health and disease begin in humans and why our immune system is set up ready on that battle front.

By Jack Kruse|July 30th, 2011|Adrenals, Anorexia and Bulimia, Autism, EMF, Fibromyalgia, Inflammation, Leaky Gut / Grain Brain, Nutrients and Supplements, Optimal Pillar 3, Optimal Pillar 5, Series: Leaky Gut, The Digestion Connection, The Leptin Prescription, The Optimal Paleo Diet|306 Comments