Inflammation

BRAIN GUT 7: INTRO TO YOUR GUT MICROBIOME

Many of you know I believe obesity if an inflammatory disease of the brain. Where this disease begins may surprise some of you. It begins in our gut flora. How does this happen? Read this link! Sub optimal bacteria which contain bacterial toxins called lipopolysaccharides (LPS) which are found in bacterial cell membranes. As gut LPS rises, it has been shown to cause a rise in serum leptin levels. Once leptin levels are raised high enough it stimulates SOCS 3 signaling in the hypothalamus to cause LR.

Brain Gut 6: Epi-Paleo Rx

This blog followed a very popular July 2012 Webinar that I put on for my members a few days ago. The webinar was over two hours long and had a lot of Q & A done after it as well. I promised my members I would get a quick blog post up for them on some of the core materials we covered. Today's blog is delivering on that promise. How to consider eating the Epi-Paleo Rx: Always Respect circadian cycles and eat according to seasonality, Lots of good quality proteins (see below), Lots of good quality fats (grass-fed/pastured animal fats - lard, tallow), Liberal uses of seafood broths and bone broth made from ocean and grass-fed animals (to heal the gut), and fermented vegetables and/or probiotics (to repopulate the gut with an Optimal Human flora)

Brain Gut #5: Paradigm Drifts Paradigm Shifts–Epi-Paleo Rx

Geeks: The implications of Brain Gut 4 mean that to develop a brain seafood is required part of the program to maintain it. Nutrients and many other environmental factors have also been found to influence epigenetic programing of our DNA either directly or indirectly via metabolic sensors. Peroxisomal proliferator-activated receptors (PPAR's), the vitamin D receptors, and the retinoid X receptors (RXR), and the retinoic acid receptors (RAR) are all examples of the nuclear receptors that interact with the brain cell membranes to control inflammation and metabolism all over our bodies. It turns out that PPAR's are the receptors that are at the crossroads of where inflammation and metabolism actually cross. These are specialized lipid sensors that pay attention to our balance of omega 6 and 3 levels. 3{a7b724a0454d92c70890dedf5ec22a026af4df067c7b55aa6009b4d34d5da3c6} of the human genome is directly or indirectly controlled by the endocrine functions of the Vitamin D system. This shows you how environmental signals are intertwined into the expression of DNA in humans. The Epi-Paleo Rx controls inflammation at a hormonal level in the brain better than the more famous paleo diet. Non Geeks: What we eat is really damn important when you have 3 lbs of lipid in your head called a brain. If you eat outside our design you get sick.

Cancer Q&A Teleseminar

Buy Q&A Call Cancer & Breast Cancer Q&A Call Only! See related products below for the Cancer Webinar Everyone has been affected by cancer. In 1900, only 3 out of 100 deaths were attributed to cancer. Breast cancer was unheard of in the first 50 years of the 20th century. Across the board, cancer was [...]

By Jack Kruse|July 11th, 2012|Cancer, Cold Thermogenesis, Inflammation, Leaky Gut / Grain Brain, Webinars and Q&A Calls|Comments Off

Hormone CPC #1: DHEA

This blog post was created for my members who just heard my webinar on bioidentical and synthetic hormone replacement. It is specifically designed to further our discussions in that talk. DHEA has been an enigma to the public and to most physicians. I never once heard about this hormone in four years of medical school, seven years of residency or in any endocrinology lecture from my training. The general public did not learn about DHEA until 1996, when its benefits were mentioned in the media and several popular books that showed up on daytime TV shows. Most in mainstream medicine continued to ignore the science these books contained because they were not found in the usual ways via journals and continuing education classes. You actually had to be on the lookout for this information. With a busy medical practice, this is no easy task. DHEA became credible to the medical establishment when the New York Academy of Sciences published a book called DHEA and Aging. That book provided scientific validation for the many life-extending effects of DHEA.

CPC #5 THE LEAKY GUT/ADRENAL FATIGUE CASE

READERS SUMMARY: HOW CAN A LEAKY GUT CAUSE ADRENAL FATIGUE? CAN OTHER THINGS COMPLICATE THIS LIKE A VIRAL INFECTION? CAN WE TREAT IT? HOW DO WE TREAT IT? CAN YOU HOPE FOR IMPROVEMENT TOO? A PATIENT TESTIMONIAL AFTER JUST 4 MONTHS OF TREATMENT We have talked at length on my forum about how a leaky [...]

By Jack Kruse|June 10th, 2012|Adrenals, Cold Thermogenesis, Epi Paleo, Epigenetics, Inflammation, Leaky Gut / Grain Brain, Optimal Pillar 4, Optimal Pillar 5, Osteoporosis, Series: CPC, The Digestion Connection, The Optimal Paleo Diet|65 Comments

Cold Thermogenesis 13: The FAQ’s

The readers of my forum asked for a FAQ's on CT and I decided it would be a good idea to make a short blog about this. They picked their top 25 questions and I decided to answer them for this blog. If you have any others, just ask in the comments section. I answer them all when I have time.

By Jack Kruse|June 2nd, 2012|Cold Thermogenesis, HCG, Hormones & Methylation, Inflammation, Longevity Principles, Menopause / Andropause, Mitochondria, Nutrients and Supplements, Optimal Pillar 2, Optimal Pillar 4, Series: Cold Thermogenesis, Series: How To, The Importance of Sleep, The Leptin Prescription|82 Comments

Cold Thermogenesis 12: Getting Back “On Board” With My Message

Well, it has been a very interesting last few days but I am not the kind of person who looks in the rear view mirror to run my race. What happened happened and it will all come out in the wash eventually. I am a person who runs their own race by looking forward via the windshield as I step on the accelerator pedal to live my life. If we focus on the past we lose sight of where we are headed and the road to Optimal. A reader of mine, Dan K, sent this gem to me, "I heard the Dalai Lama once say in a lecture that our worst enemies are your greatest teachers because they allow you to examine the emotions of anger and revenge and then to transcend them. They give you the exact tools you need to elevate yourself to the spiritual energies that eliminate problems and provide solutions." So today, I am moving toward the Paleo template and away from the "Paleo Radical Insurgency" who is steering the community into an abyss. There are too many people who need help and not the surrounding drama. The time has come to become, Epi-paleo, a term I mentioned at my Paleo fx speech, and that is what I will be building here on my blog and forum from here on out. An event that appears to be a tragedy to one, might reveal the seeds of unlimited opportunity for another. On the Low Carb cruise I was going to present some of the things that happened in my mind at the base of Michelangelo's David in help me realize that the missing piece to the obesity and insulin resistant story was the "off switch" in how we make fat and how we continue to make fat cells. Gary Taubes was scheduled to be the featured speaker for the cruise, but he could not attend, so Jimmy Moore asked me to step in his role. Gary wrote a book called, "Why we get Fat" but I clearly am not Gary Taubes, and I was not here to tell them why we get fat…I was going to tell you how to reverse being fat and insulin resistant…because unlike, Mr. Taubes, I have done it myself and pretty successfully. Obese humans have a difficult life to live. I know the life they live because I was one of them for close to decade. It is very hard to take advice from someone who has never had obesity. To understand the mindset one has to have walked in the shoes. Most of the people giving out advice however have not had a successful track history of losing the weight and keeping it off. The reason for this is they are prisoners to modern dogma of fatness.

By Jack Kruse|May 8th, 2012|Cold Thermogenesis, Diabetes, Epi Paleo, Epigenetics, Inflammation, Longevity Principles, Optimal Pillar 2, Optimal Pillar 4, Optimal Pillar 5, Series: Cold Thermogenesis, The Leptin Prescription, The Optimal Paleo Diet|Comments Off

BOOK REVIEW 1: Make Shift Happen & Sweet Potato Power

READERS SUMMARY: 1. WHAT BOOKS AM I READING NOW AND WHY? 2. WHY AM I WRITING BOOK REVIEWS IN A BLOG? 3. I THINK SOME PEOPLE HAVE IDEAS WE ALL NEED TO SHARE WITH THE WORLD? 4. I RARELY DO BOOK REVIEWS UNLESS THE BOOKS ARE WORTH IT, THESE TWO ARE. It's time to [...]

By Jack Kruse|May 4th, 2012|Epi Paleo, Epigenetics, Heart Disease, Hormones & Methylation, Inflammation, Longevity Principles, Optimal Pillar 4, Recipes & Cooking, Series: Miscellaneous, The Optimal Paleo Diet|Comments Off

Cold Thermogenesis 11: Paleo FX To Practice

Today, I want to introduce you to someone who is a true 'Paleo leader' by stepping up to the the challenge I put to our community at PaleoFx conference recently held in Austin, Tx. Kevin Cottrell is one of the co founders of Paleo Fx. The leaders of Paleo fx have to be commended because the conference they were able to put on in 150 days of prep time was nothing short of remarkable. The conference exceeded all my expectations and the reviews of many attendees have been stellar. The future of this community is tied to clinical application of what the science continues to show in the literature. For assimilation of the Ancestral Lifestyle to become mainstream we need to have more clinical conferences like Paleo fx, and we need to take them globally. Today, I am breaking new ground and presenting to you my first guest blog written by Mr. Kevin Cottrell, who has agreed to share his personal story and personal medical history with all of you so that he may help you in some way. I think what he has agreed to do here is the most noble and worthy things to do to help our community and mankind. I am indebted to him for this chance to publish his story for you to consider. The following post is written by Kevin, in his words, to share with you and yours, to help open your eyes and challenge your "own dogma and current intuition' to help you reach for optimal health.